Journal: Journal of Bone and Joint Infection
Article Title: Determination of Tobramycin and Vancomycin Exposure Required to Eradicate Biofilms on Muscle and Bone Tissue In Vitro
doi: 10.7150/jbji.29711
Figure Lengend Snippet: Minimum inhibitory concentration (MIC) and fractional inhibitory concentration (FIC) index for musculoskeletal associated biofilms. FIC index values indicate synergistic (≤0.5), indifferent (0.5-4), or antagonistic (≥4) drug interactions.
Article Snippet: Three antimicrobial regimens were investigated: tobramycin alone (TOB; tobramycin sulfate USP, Spectrum Chemical), vancomycin alone (VANC; vancomycin hydrochloride USP, Chem-Impex International Inc.), and tobramycin/vancomycin 1:1 combination by mass (TOB+VANC).
Techniques: Concentration Assay